New Treatment for Alcohol Use Disorder

alcohol use disorder

This month we are talking about alcohol, because April is Alcohol Awareness Month. The annual occurrence involves a number of events taking place throughout the country, with the aim of increasing public awareness and understanding about the dangers of alcohol use. Alcohol Awareness Month is sponsored by the National Council on Alcoholism and Drug Dependence, Inc. (NCADD) – the leading advocacy organization in the world addressing alcoholism and drug dependence since 1942. This year’s Alcohol Awareness Month theme is: “Talk Early, Talk Often: Parents Can Make a Difference in Teen Alcohol Use.”

Having an unhealthy relationship with alcohol during adolescence can lead to an alcohol use disorder as early as young adulthood. Parents who have open, honest conversations with their children drastically reduce the likelihood of their kids using drugs or alcohol. The more teenagers know about the dangers commonly associated with alcohol use, the greater the chance they will stay away from the insidious substance.

“Alcohol and drug use is a very risky business for young people,” says Andrew Pucher, President and Chief Executive Officer of NCADD, “and parents can make a difference. The longer children delay drinking and drug use, the less likely they are to develop any problems associated with it. That’s why it is so important to help your child make smart decisions about alcohol and drugs.”

Unfortunately, many young adults are already living with an alcohol use disorder (AUD), which is why researchers have a huge incentive to develop effective treatments. Residential treatment centers give people struggling with alcohol the best shot at recovery, but there are times when medications are used to help prevent relapse, such as:

  • Acamprosate
  • Naltrexone
  • Disulfiram

While some people recovering from alcoholism respond well to the aforementioned medications, others have not been so fortunate. Researchers from QUT’s Institute of Health and Biomedical Innovation may have found a new treatment for AUD, and the beta blocker pindolol has already been approved by the Food and Drug Administration (FDA), Science Daily reports. The findings were published in Addiction Biology, the Journal of the Society for the Study of Addiction.

“Drugs currently used for AUDs (alcohol use disorders) — acamprosate, naltrexone and disulfiram — have limited success — so this is a ground-breaking development with enormous potential,” said Professor Bartlett who is based at the Translational Research Institute. “In an internationally-significant breakthrough, our study showed pindolol was able to reduce ethanol/alcohol consumption, particularly in relation to binge drinking, a key behaviour observed in human alcohol dependence.”

Alcohol Use Disorder Screening

alcohol use disorder

Alcohol use disorder (AUD) affects millions of Americans, a disorder which can have serious impact on one’s health and can be fatal. Without effective, evidence-based treatments, the chances of recovery are slim. Sadly, many young adults have an AUD which usually arose in their teenage years. Preventing teenage alcohol misuse and abuse is crucial, and doctors can play a huge role in intervening early on.

New research has found that physicians who ask teens just one question about drinking frequency in the past year can help them determine who is at risk for developing an AUD down the road, according to the National Institute on Alcohol Abuse and Alcoholism (NIAAA) press release. The study involved almost 1,200 young people ages 12 to 20. The findings were published in the Journal of Pediatrics.

“Primary care physicians are encouraged to screen adolescents for alcohol problems, yet many do not, citing time constraints and other issues,” NIAAA Director George Koob, PhD said in a news release. “This study demonstrates that simple screening tools such as those in NIAAA’s Youth Guide are efficient and effective.”

Using a computer-based questionnaire at a primary care clinic, the teens involved in the study were asked about how much alcohol they use and were screened for an AUD, the press release reports. The researchers found that 10 percent of those over age 14 met the diagnostic criteria for an AUD. The NIAAA funded study found that 44 percent of teens between 12 and 17 years old who had at least one drink on three or more days in the past year met the criteria for AUD. But everyone who drank that much was at risk for alcohol problems. Thirty-one percent of 18-20 year olds who reported 12 or more drinking days in the last year were found to have an AUD.

“This finding confirms that a single question can be an effective screen for AUD,” said lead researcher Duncan B. Clark, MD, PhD, Professor of Psychiatry at the University of Pittsburgh Medical Center.

If you are a young adult and believe that you have a problem with alcohol, please contact Harmony Foundation. Our Young Adult Recovery Track (YART) is specifically tailored for treating young adults with substance use disorders, let us help you begin the journey of recovery.

Nonviolent Drug Offenders See Light Again

Addiction is not a crime! It isn’t a moral failing or a lack of constitution. Addiction is a disease of the mind that requires treatment and a program of maintenance, if recovery is to be possible. For decades, the United States government’s solution to addiction was locking up “offenders” and essentially throwing away the key. Even if a non-violent drug offender was released, the likelihood of recidivism was staggering.

Handcuffs and cell bars do not treat addiction, they only serve to put a scientifically accepted mental illness on the back burner; the disorder simmers until the day of release, at which time it comes forward and is brought to a rolling boil. Without the tools and resources necessary to remain abstinent, the vast majority will find themselves behind bars again. It is a vicious cycle that has been the status quo for too long.

Over the last decade, lawmakers have slowly come to terms with the fact that they can no longer treat addiction, and those who suffer from the disease, the way they have in the past; fear of punishment does little to detract addicts from continuing to use. Politicians from both sides of the aisle have begun to push for changes with regard to mandatory minimum sentences, rules that take sentencing out of the hands of judges. Right now, as these words are written, thousands of people are sitting behind bars for anywhere from 20 years to life – the result of nonviolent drug offenses.

Fortunately, we may be able to learn from the mistakes of our past, doing away with draconian mandatory minimum sentences and releasing those who are serving unjust terms for the crime of addiction. President Obama has done a lot in his tenure to undo some of our mistakes, granting clemency to hundreds of nonviolent drug offenders. In fact, the President has commuted the sentences of 248 prisoners thus far, more prisoners than the last six presidents put together, The New York Time reports. On Wednesday, the President commuted 61 sentences, more than one third of which were serving life sentences.

“Most of them are low-level drug offenders whose sentences would have been shorter if they were convicted under today’s laws,” President Obama said on his Facebook page. “I believe America is a nation of second chances, and with hard work, responsibility, and better choices, people can change their lives and contribute to our society.”

A Vaccine for Heroin?

heroin

The American prescription opioid epidemic has affected millions of Americans and their loved ones. Efforts to curb painkiller abuse had the unintended effect of leading to a scourge of heroin use – as the drug is often times cheaper, stronger and easier to acquire in the wake of prescription opioid crackdowns. Heroin abuse has become a major public health concern in both urban and rural America, due to the rise in both addiction and overdose death rates. While there is help available in the forms of treatment and 12-Step recovery, relapse rates are particularly high among opioid addicts.

Scientists continue to develop new methods intended to give addicts the best shot at successful recovery, and believe it or not, in the near future there may be a vaccine available that will prevent people from getting high if they use. Research was published last month that dealt with developing a vaccine that would prevent people from getting high if they use the powerful opioid narcotic fentanyl – an analgesic that is 80 to 100 times more potent than morphine, and 50 times stronger than heroin.

What’s more, clandestine laboratories are manufacturing fentanyl which is then being mixed with heroin to make it more potent. Heroin users are often unaware of the presence of fentanyl, an ignorance that can prove fatal. Admixtures of heroin fentanyl can severely depress respiratory function, which can result in death.

Working with mice, researchers were able to inject the animals with booster shots that would train their immune systems to attack the fentanyl molecules in the bloodstream before the drug crossed the blood-brain barrier resulting in euphoria or potential overdose, The Daily Beast reports. Additionally, when the researchers injected the mice with lethal doses of fentanyl, the mice survived.

“The idea that [the researchers] can make an effective vaccine is very cool. It’s a good accomplishment,” says Phil Skolnick, director of the Division of Pharmacotherapies and Medical Consequences of Drug Abuse at the National Institute on Drug Abuse (NIDA), who was not involved in the study. “You have to trick the body, and it requires a fair amount of trickery.”

If the human clinical trials are successful, it could eventually lead to the development of a heroin vaccine. The vaccines would be specific to particular drug molecules. If people in recovery from heroin addiction are vaccinated, it could significantly deter relapse because the user would know that they will not experience the desired euphoric affect.

Until such time, the best opportunity of successful recovery rests on effective, evidence-based addiction treatment programs. If you are battling with prescription opioid and/or heroin addiction, please contact Harmony Foundation to begin the journey of recovery.

Testing Cannabis Edibles for Potency

cannabis-edibles

Last month we wrote about what is known as “marijuana tourism,” the act of traveling to states where recreational marijuana use is legal. With four states allowing adult cannabis use, there are a number of options for people who want to experience the end of marijuana prohibition first hand. A number of marijuana tourists are not regular users, and may or may not have ever used extremely potent strains of marijuana or edibles that can be purchased at pot shops. In the state of Colorado, researchers found that emergency rooms have seen a surge of visits by out-of-staters experiencing marijuana-related medical problems. Many of the incidents involved marijuana edibles which, it turns out, can be difficult to gauge with regard to the dosage of tetrahydrocannabinol (THC) present in such products.

There is a growing concern about inconsistent and inaccurate dosage information listed on the labels of marijuana edibles, which can mislead potential users. In response, scientists have developed a new method for measuring the level of marijuana compounds present in edibles, Science Daily reports. The scientists exhibited their work this week at the 251st National Meeting & Exposition of the American Chemical Society (ACS).

“Producers of cannabis edibles complain that if they send off their product to three different labs for analysis, they get three different results,” says Melissa Wilcox, who is at Grace Discovery Sciences. “The point of our work is to create a solid method that will accurately and reliably measure the cannabis content in these products.”

Jahan Marcu, Ph.D., from Americans for Safe Access and vice-chair of the newly formed ACS Cannabis Subdivision, points out that inconsistent and inaccurate labeling is important because eating cannabis is different than smoking, according to the article. Cannabis edibles are metabolized differently than when marijuana is inhaled, which can produce a stronger high that comes on slowly and has a longer lasting effect.

“It’s a lot easier for an individual to control their dose when smoking,” Wilcox says. “The effects of edibles can take a while to happen. You eat them, and then wait to see how you feel in an hour or two. If you ingested too much, you could be in for an unexpectedly bad experience.”

The current method employed for analyzing the potency of edibles involves using a high performance liquid chromatography (HPLC), the article reports. Marcu notes that HPLCs were not designed to have food injected into them, the sugars, fats and starches hinder the machines ability to produce accurate results. In order to combat the problem, the researchers developed a technique that separates the cannabinoids from the rest of the food. They then inject a liquid containing only the marijuana compounds into the HPLC.

People traveling to take part in the marijuana experience should be fully aware of the risks present with cannabis use. While the drug is legal for both medical and recreational use in a number of states, it does not mean that the drug cannot have adverse effects on people and it can also be habit forming. If you believe that cannabis use is negatively affecting your life, please contact Harmony Foundation.

Senate Votes On Comprehensive Addiction and Recovery Act

CARA

With presidential candidates crisscrossing the country discussing how to handle the prescription opioid and heroin epidemic, lawmakers in D.C. are also hard at work to combat the problem as well. It is no secret that democrats and republicans often disagree about major issues; one thing lawmakers from both sides of the aisle can agree on is that something needs to be done – sooner rather than later.

This week, the Senate voted in favor (86-3) of the Comprehensive Addiction and Recovery Act (CARA), a bill which would give federal grants to states and local governments to help fund the fight against our nation’s crippling health crisis, USA Today reports. If a final vote on the bill’s passage is in favor, it will give the Attorneys General the power to fund improvements in:

  • Prescription Drug Monitoring Programs
  • Addiction Treatment
  • Prevention
  • Education

CARA was sponsored by Sheldon Whitehouse of Rhode Island, a Democrat, and Rob Portman of Ohio, a Republican, according to the article. A bill which would put at least $80 million towards treatment, prevention and recovery. While the bill’s support is definitely a step in the right direction, the bill would not actually fully fund $725 million needed to accomplish everything that its sponsors intended. Unfortunately, an effort to add $600 million in emergency funding to the bill was blocked last week.

One of the states affected the most by the opioid crisis is New Hampshire. While a small state, they are losing lives every day to overdoses. The effort to garner the additional funding was led by Senator Jeanne Shaheen, D-N.H.

“There is simply no excuse for Congress providing emergency funding for the Ebola and swine flu epidemics, while ignoring an opioid crisis that’s killing a person a day in the Granite State,” said Shaheen.

If you are struggling with opioid addiction, please contact Harmony Foundation. We can help you build the foundation for sustained addiction recovery.

New FDA Commissioner Supports Abuse-Deterrent Opioids

abuse-deterrent-opioids

It does not matter how someone uses prescription opioids, they can be dangerous and potentially lead to a deadly overdose. However, it could easily be argued that the greatest risk is associated with intravenous (IV) use; opioid addicts will crush their pills, mix the powder with water and inject. In order to combat the use of opioid narcotics in unintended ways, pressure was put on pharmaceutical companies to develop formulations of their painkillers that are harder to abuse – known as abuse-deterrent opioids.

Critics of such efforts argue that harder-to-abuse painkillers are merely a band-aid, and have little effect on the opioid epidemic. While the new formulations are more difficult to use, addicts often find their way around tamper resistors and/or turn heroin as a cheaper, stronger alternative. Nevertheless, such arguments can easily be countered with ‘anything is better than nothing.’

The U.S. Food and Drug Administration (FDA) has a new commissioner who has vowed to support abuse-deterrent opioid efforts, the Associated Press reports. Dr. Robert Califf told a panel of FDA advisers that he is pledging to do “everything possible under our authority to prevent abuse, save lives and treat dependence.”

The new commissioner’s declaration is just one facet of an interagency effort to end the American opioid epidemic. However, Califf made clear that the FDA alone cannot resolve the current crisis, according to the article. Since 2010, Califf’s agency has approved five abuse-deterrent opioids, and there is reportedly another 20 such drugs in development. FDA Commissioner Califf plans to work with outside advisers and he has a comprehensive plan for addressing the prescription opioid scourge, which claims as many as 44 lives per day.

He stated that the agency will add more cautionary warning labels to the opioid narcotics prescribed the most, the article reports. What’s more, the FDA will encourage the safe disposal of unused medications, which will prevent narcotics from ending up in the wrong hands.

“What we can do is work with prescribers, professional associations, patient advocates and state and local partners — essentially the entire country — to encourage safe use and disposal of opioid medications,” said Califf. 

If you or a loved one struggles with prescription opioid and/or heroin addiction, please contact Harmony Foundation. We have been helping people break the cycle of addiction for decades, teaching people about the resources needed for a living a life on the road of recovery.

Marijuana Tourists’ Emergency Room Visits

marijuana

When it comes to which mind altering substances carry the greatest health risk it is probably fair to say that most Americans would agree that marijuana is at the bottom of the list – as is evident by the continued lightening of restrictions when it comes to the use of cannabis. In the last 20 years, since California became the first state to legalize the use of medical marijuana, more and more states have hopped on the “green train,” medical marijuana is now legal in 24 states and Washington D.C. Four of those states and Washington, D.C. have also legalized adult recreational use, with more states expected to follow suit this November.

The State of Colorado is one of the four states that have legalized adult cannabis use, and in 2014 sale began throughout the state. Legalization, like one might expect, has brought about a surge in marijuana tourism, that is people who would like to walk into a store and buy marijuana, just like one would by a six-pack of beer. The novel experience is a not without risk, a new report has shown a spike in emergency room visits involving out-of-state visitors experiencing marijuana-related medical problems, HealthDay reports. Between 2013 and 2014, the number of marijuana tourists visiting the University of Colorado Hospital emergency room doubled, according to a research letter published in the New England Journal of Medicine.

“People in Colorado are becoming more experienced with use of these products,” said study co-author Dr. Andrew Monte, an assistant professor of emergency medicine at the University of Colorado School of Medicine in Aurora. “Sometimes visitors to the state, it’s more difficult to get the educational information in their hands. They may be less experienced with the particular products in the state. They haven’t been exposed to the deluge of public health messaging.”

While marijuana may be perceived as being a benign substance, a number of marijuana products contain extremely high levels of tetrahydrocannabinol (THC) – the main psychoactive ingredient that produces the high marijuana users experience. Monte points out that the majority of ER visits are the result of marijuana affecting pre-existing medical conditions, according to the article. Cannabis edibles are also responsible for a large number of emergency room visits, which if too much is consumed can cause severe vomiting.

It is important to keep in mind that on top of physical health risks, marijuana can become habit forming and potentially lead to addiction. If marijuana is negatively impacting your life, please contact Harmony Foundation for assistance.

Young Adult Non-Medical Adderall Use

Adderall

Amphetamine salts, such as Ritalin ® or Adderall ®, are prescribed by physicians to treat attention deficit hyperactivity disorder (ADHD). While prescription stimulants can be an effective ADHD treatment, the drugs are commonly diverted and used by people who want an edge for studying. Others will use the drugs to get high or for extra energy for partying longer. Stimulants are highly addictive, and abuse can lead to a number of serious health problems. What’s worse, the majority of stimulant users are unaware of the risk amphetamines pose.

The non-medical use of drugs like Adderall is especially common among young adults, typically those enrolled college. Small doses of amphetamines can increase people’s focus, helping them study for prolonged periods of time. In heavy amounts, the drugs can lead to life threatening side effects, including nausea, vomiting and seizures. In fact, new research shows that while prescriptions for stimulants have remained fairly level in recent years, non-medical use of Adderall by young adults has risen by 67 percent and associated emergency room visits rose by 156 percent, UPI reports. The study was conducted by researchers at Johns Hopkins University and was published in the Journal of Clinical Psychiatry.

Unfortunately, many young adults do not view the use of stimulants as being dangerous. What’s more, amphetamine narcotics are most commonly acquired from one’s friends and family. The researchers point out that misconceptions about the use of Adderall can be deadly, resulting in high blood pressure and even a stroke.

“[The study] suggests that the main driver of misuse and emergency room visits related to the drug is the result of diversion — people taking medication that is legitimately prescribed to someone else,” said former Johns Hopkins student Dr. Lian-Yu Chen, now a researcher at National Taiwan University Hospital. “Physicians need to be much more aware of what is happening and take steps to prevent it from continuing.”

If you are struggling with non-medical amphetamine use, it is vital you seek help immediately, please contact Harmony Foundation. Breaking the cycle of addiction is a difficult process. We offer the most effective treatment environment for young adults, we can help you begin the healing process and the journey into recovery.

Ignition Interlocks Stop Over A Million Drunk Drivers

drunk-driving

The major substance use news these days deals primarily with the opioid epidemic in America; we need to remember that there are plenty of other addictive mind altering substances that can wreak havoc on one’s life. Alcohol remains to be the most commonly used drug in America, alcohol is pervasive and deeply rooted in our society. It’s a substance that takes an enormous toll on both the public health and the economy; it’s responsible for thousands of deaths every year from alcohol related illness and driving under the influence (DUI).

While the Centers for Disease Control and Prevention (CDC) reports that 44 people die of an overdose every day, a staggering figure to be sure, the agency also reports that in the United States almost 30 people die in motor vehicle crashes that involve alcohol-impaired drivers. Despite the fact that even teenagers are aware that driving under the influence is unsafe, people continue to put their lives and the lives of others in their hands in danger, which often times ends in tragedy.

Over the last decade there have been a number of efforts made to mitigate both the effects and the likelihood of drunk driving. Those who are caught drunk driving face heavy financial penalties, possible jail time, and loss of license for varying lengths of time. What’s more, in many states those convicted of DUIs are required to have ignition interlock devices installed in their vehicle. The instruments keep the car from starting unless the driver blows into a breathalyzer; if alcohol is detected the device will prevent the car from starting and the driver will have to go back to court and may be sent to jail.

A new report highlights the success of requiring interlocks, showing that the devices have stopped more than 1.77 million people from attempting to drive drunk since 1999, the Associated Press reports. The findings come from data released by 11 major ignition interlock manufacturers.

“MADD knows ignition interlocks save lives, and they could save even more lives if every offender is required to use the device after the first arrest,” said Colleen Sheehey-Church, the president of Mothers Against Drunk Driving. 

Currently, twenty-five states require ignition interlocks for any drunk driving offense, even for a first-time DUI, according to the article. All 50 states have passed some kind of ignition interlock law, but some are much stricter than others and MADD would like to see the states with softer laws, toughen up.

It is often the case that people convicted of DUIs are required to attend 12-step recovery meetings. That is not to say that everyone who gets a DUI has an alcohol use disorder, and most of those who are required to go to meetings do so begrudgingly; however, there are some who are required to attend meetings of Alcoholics Anonymous that realize that they do have a problem with alcohol and are willing to give recovery a chance. While getting a DUI is never fun, it can be the catalyst that leads to recovery.